Case Study
QuidelOrtho
Managing the full lifecycle of a point-of-care diagnostic platform for more than 30 years.
Product
Triage MeterPro®
Customer:
QuidelOrtho Corporation
Market/Application:
Immunoassay/Cardiovascular Disease/Drug Substance Abuse
From initial concept to global deployment, LRE has supported the Triage® System through more than 30 years of development, production and evolution.
QuidelOrtho partnered with LRE at the earliest proof-of-concept stage to bring a bold vision to life: a cartridge-based analyzer designed to redefine point-of-care diagnostics. Through close collaboration, this vision was translated into the Triage® System, the world’s first point-of-care cardiac biomarker testing system.
Solving the engineering challenges
By combining custom optical design, breakthrough calibration techniques and regulatory-ready development, we have delivered a fully integrated, scalable solution.
Supporting continuous evolution
Today, thousands of systems are deployed globally, supported by more than 30 years of ongoing lifecycle partnership, including multiple platform evolutions, continuous performance enhancements and proactive supply-chain stewardship. The result is a long-standing collaboration delivering reliability at scale and sustained market impact.
Major Challenges
- Standard laser collimators failed to produce homogeneous lines
- Non-linear motion was a constraint
- No stable fluorescence standards available
- Lack of internal standards for instrument calibration
Our Solution
- Custom-designed laser collimator tailored to application needs
- Calibration procedure developed to compensate for optical offsets
- Fluorescence standard created using immobilized particles
- Statistical calibration method implemented for accuracy and consistency
- Ongoing performance monitoring and regular updates
- Comprehensive documentation and regulatory compliance ensured
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Mid-life upgrades:
– Three generations of redesigns to enhance performance and reliability - Long-life upgrades:
– Introduction of new tooling for five critical components
– Robust obsolescence management (PCN, ECR, LTB)
– Proactive supply chain management to ensure continuity and quality
– Mainboard, controller, production hardware, and software
Proven Expertise
- Transformation of a cartridge-based analyzer concept into the world’s first point-of-care cardiac biomarker testing system
- End-to-end development from early concept through industrialization, series manufacturing, and lifecycle management
- Deep expertise in optical systems, calibration methods, and fluorescence-based diagnostics
- Long-term partnership aligned with evolving customer needs, including ownership transitions
- Proven product lifecycle management and sustained performance over more than 30 years