Success Story
QuidelOrtho
From idea to industrialization, managing the full lifecycle of a point-of-care diagnostic platform for diverse medical conditions for more than 30 years.
Product
Triage MeterPro®
Customer:
QuidelOrtho Corporation
Market/Application:
Immunoassay/Cardiovascular Disease/Drug Substance Abuse
QuidelOrtho has partnered with LRE at the earliest proof-of-concept stage to bring a bold vision to life: a cartridge-based analyzer designed to redefine point-of-care diagnostics. Through close collaboration, this vision was translated into the Triage® System, the world’s first point-of-care cardiac biomarker testing system.
By combining custom optical design, breakthrough calibration techniques, and regulatory-ready development, we have delivered a fully integrated, scalable solution.
Today, thousands of systems are deployed globally, supported by more than 30 years of ongoing lifecycle partnership — including multiple platform evolutions, continuous performance enhancements, and proactive supply-chain stewardship. The result is a long-standing collaboration that showcases engineering excellence, reliability at scale, and sustained market impact.
Major Challenges
- Standard laser collimators failed to produce homogeneous lines
- Non-linear motion was a constraint
- No stable fluorescence standards available
- Lack of internal standards for instrument calibration
Our Solution
- Custom-designed laser collimator tailored to application needs
- Calibration procedure developed to compensate for optical offsets
- Fluorescence standard created using immobilized particles
- Statistical calibration method implemented for accuracy and consistency
- Ongoing performance monitoring and regular updates
- Comprehensive documentation and regulatory compliance ensured
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Mid-life upgrades:
– Three generations of redesigns to enhance performance and reliability - Long-life upgrades:
– Introduction of new tooling for five critical components
– Robust obsolescence management (PCN, ECR, LTB)
– Proactive supply chain management to ensure continuity and quality
– Mainboard, controller, production hardware, and software
Proven Expertise
- Transformation of a cartridge-based analyzer concept into the world’s first point-of-care cardiac biomarker testing system
- End-to-end development from early concept through industrialization, series manufacturing, and lifecycle management
- Deep expertise in optical systems, calibration methods, and fluorescence-based diagnostics
- Long-term partnership aligned with evolving customer needs, including ownership transitions
- Proven product lifecycle management and sustained performance over more than 30 years